Scientific Publications Since 2017 (from >230; see Pubmed bibliography)

Wong D, Nielsen TB, Bonomo RA, Pantapalangkoor P, Luna B, Spellberg B.  Clinical and Pathophysiological Overview of Acinetobacter Infections: A Century of Challenges.  2017.  Clin Microbiol Reviews.  30:409-447.  PMCID: PMC5217799


Marshall S, Hujer AM, Rojas LJ, Papp-Wallace KM, Humphries RM, Spellberg B, Hujer KM, Marshall EK, Rudin SD, Perez F, Wilson BM, Wasserman RB, Chikowski L, Paterson DL, Vila AJ, van Duin D, Kreiswirth BN, Chambers HF, Fowler VG Jr, Jacobs MR, Pulse ME, Weiss WJ, Bonomo RA.  Can ceftazidime/avibactam and aztreonam overcome β-lactam resistance conferred by metallo-β-lactamases in Enterobacteriaceae?  2017.  Antimicrob Agents Chemother.  61:e02243-16.


Spellberg B.  Sacubitril-Valsartan in Heart Failure.  2017.  Ann Int Med.  166:680.

Cheng BL, Nielsen TB, Pantapalangkoor P, Zhao F, Lee JC, Montgomery CP, Luna B, Spellberg B, Daum RS.  Evaluation of serotypes 5 and 8 capsular polysaccharides in protection against Staphylococcus aureus in murine models of infection.  2017.  Human Vaccine Immunother.  13:1609-14.  PMCID: PMC5512765.


Thompson GR III, Blair J, Wang S, Bercovitch R, Bolaris M, Van Den Akker D, Lopez R, Heidari A, Catanzaro A, Cadena J, Chin-Hong P, Spellberg B, Johnson R.  Adjunctive Corticosteroid Therapy in the Treatment of Coccidioidal Meningitis.  2017.  Clin Infect Dis.  65:338-41.


Luna BM, Ulhaq A, Yan J, Pantapalangkoor P, Nielsen T, Davies B, Actis L, Spellberg B.  Selectable markers for use in genetic manipulation of extreme drug resistant (XDR) Acinetobacter baumannii HUMC1.  2017.  mSphere.  2(2). pii: e00140-17.  PMCID: PMC5422034


Spellberg B.  Preserving the Health of the Public and Our Specialty.  2017.  Clin Infect Dis.  65:1597.


Nielsen TB, Pantapalangkoor P, Luna BM, Bruhn KW, Yan J, Dekitani K, Hsieh S, Yeshoua B, Pascual B, Vinogradov E, Hujer KM, Domitrovic TN, Bonomo RA, Russo TA, Lesczcyniecka M, Schneider T, Spellberg B.  Monoclonal Antibody Protects against Acinetobacter baumannii Infection by Enhancing Bacterial Clearance and Evading Sepsis.  2017.  J Infect Dis.  216:489-501.  PMCID: PMC5853763.


Nielsen TB, Pantapalangkoor P, Yan J, Luna BM, Dekitani K, Bruhn KW, Tan B, Junus J, Bonomo RA, Schmidt AM, Everson M, Duncanson F, Doherty TM, Lin L, Spellberg B.  Diabetes Exacerbates Infection via Hyperinflammation by Signaling through TLR4 and RAGE.  2017.  mBio.  8:e00818-17.  PMCID: PMC5565964.

Spellberg B.  Mucormycosis pathogenesis: Beyond Rhizopus.  2017.  Virulence.  8:1481-2.  PMCID: PMC5810489.


Barnes MD, Winkler ML, Taracila MA, Page MGP, Desarbre E, Kreiswirth BN, Shields RK, Nguyen MH, Clancy C, Spellberg B, Papp-Wallace KM, Bonomo RA.  Klebsiella pneumoniae carbapenemase-2 (KPC-2), substitutions at Ambler position Asp179, and resistance to ceftazidime-avibactam: unique antibiotic resistant phenotypes emerge from β-lactamase protein engineering.  2017.  mBio.  e00528-17.


Wald-Dickler N, Holtom P, Spellberg B.  Busting the Myth of “Static vs. Cidal”: A Systematic Literature Review.  2017.  Clin Infect Dis.  66:1470-4.  PMCID: PMC5905615.


Coffey C Jr, Carter V, Wei E, Hutcheon D, Gruen JP, Anonas-Ternate A, Sandoval R, Marquez A, Sarff L, Spellberg B.  No More “Code Black”: Intervention to Improve Inpatient Flow at a Large Public Hospital.  2018.  Am J Med.  131:371-376.


Spellberg B.  The Maturing Antibiotic Mantra: “Shorter Is Still Better”.  2018.  J Hosp Med.  13:361-2.

Yen C, Holtom P, Butler-Wu S, Wald-Dickler N, Shulman I, Spellberg B.  Reducing Clostridium difficile colitis rates via cost-saving diagnostic stewardship.  2018.  Infection Control Hospital Epidem.  39:734-6.


Coffey C, Cho E, Wei E, Luu A, Ho M, Amaya R, Pecson M, Dalton F, Kahaku D, Spellberg B, Sener S.  Lean methods to improve operating room elective first case on-time starts in a large, urban, safety net medical center.  2018.  Am J Surg.  216:194-201.


Tchesnokova VL, Rechkina E, Larson L, Ferrier K, Weaver JL, Schroeder DW, She R, Butler-Wu SM, Aguero-Rosenfeld ME, Zerr D, Fang FC, Ralston J, Riddell K, Scholes D, Weissman S, Parker K, Spellberg B, Johnson JR, Sokurenko EV.  Rapid and Extensive Expansion in the U.S. of a New Multidrug-Resistant Escherichia coli Clonal Group, Sequence Type ST1193.  Clin Infect Dis.  2018.  68:334-7.


Nielsen TB, Yan J, Luna B, Spellberg B.  Murine Oropharyngeal Aspiration Model of Ventilator-Associated and Hospital-Acquired Bacterial Pneumonia.  2018.  JoVE.  28 (136). PMCID: PMC6102004.


Gaffin N, Spellberg B.  Procalcitonin Trial Does Not Reflect Clinical Practice.  2018.  New Eng J Medicine.  379:1972-3.


Yadav K, Masuda E, Minejima E, Spellberg B.  Expected Practice as a Novel Antibiotic Stewardship Intervention.  2018.  Open Forum Infect Disease.  6:ofy319.  PMCID: PMC6324551.


Wong D, Holtom P, Spellberg B.  Osteomyelitis complicating sacral pressure ulcers: whether or not to treat with antibiotic therapy.  2019.  Clin Infect Dis.  68:338-42. PMCID: PMC6594415.


Choi YJ, Kim S, Nielsen TB, Yan J, Lu A, Ruan J, Remold-O’Donnell E, Lee H-R, Wu H, Spellberg B, Jung JU.  SerpinB1-mediated checkpoint of inflammatory caspase activation.  2019.  Nat Immunol.  20:276-287.  PMCID: PMC6450391.

Wald-Dickler N, Spellberg B.  Short Course Antibiotic Therapy—Replacing Constantine Units with “Shorter Is Better”.  2019.  Clin Infect Dis.  ePub.

Minejima E, Mai N, Bui N, Mert M, She RC, Nieberg P, Spellberg B, Wong-Behringer A.  Defining breakpoint duration of Staphylococcus aureus bacteremia predictive of poor outcomes.  2019.  Clin Infect Dis.  ePub.


Ambrose PG, VanScoy BD, Luna BM, Yan J, Ulhaq A, Nielsen TB, Rudin S, Hujer K, Bonomo RA, Actis L, Skaar E, Spellberg B.  Apotransferrin in Combination with Ciprofloxacin Slows Bacterial Replication, Prevents Resistance Amplification, and Increases Antimicrobial Regimen Effect.  2019.  Antimicrobial Agents Chemother.  ePub.  PMCID: PMC6496049.


Luna BM, Ershova K, Yan J, Ulhaq A, Nielsen TB, Hsieh S, Pantapalangkoor P, Van Scoy B, Ambrose P, Rudin S, Hujer K, Bonomo RA, Actis L, Skaar EP, Spellberg B.  Adjunctive transferrin to reduce the emergence of antibiotic resistance in Gram-negative bacteria.  2019.  J Antimicrob Chemother.  74:2631-9.  PMCID: PMC6736376.


Luna BM, Nielsen TB, Cheng B, Pantapalangkoor P, Yan J, Boyle-Vavra S, Bruhn KW, Montgomery C, Spellberg B, Daum R.  Vaccines Targeting Staphylococcus aureus Skin and Bloodstream Infections Require Different Composition.  2019.  PloS One.  14(6):e0217439.  PMCID: PMC6557488.

Cornely OA…Spellberg B…Chakrabarti A (>50 authors total).  Global Guideline for the Diagnosis and Management of Mucormycosis: An initiative of the ECMM in cooperation with ESCMID/EFISG.  2019.  Lancet Infect Dis.  In Press.**


Adaptive Platform Trials Coalition (Collaborators listed alphabetically, Angus D…Spellberg B…Woodcock J).  Adaptive Platform Trials: Definition, Design, Conduct, and Reporting Considerations.  2019.  Nature Rev Drug Discovery.  ePub.


Spellberg B, Rice LB.  Duration of Antibiotic Therapy: Shorter is Better.  2019.  Ann Int Med.  ePub.  PMCID pending


Chau E, Sarkarati M, Spellberg B.  Adenosine Deaminase diagnostic testing in Pericardial Fluid.  2019.  JAMA.  322:163-4. PMCID: PMC6697089.


Nielsen TB, Brass EP, Gilbert DN, Bartlett JG, Spellberg B.  Sustainable Antibiotic Discovery and Development--Is a Nonprofit Approach the Future?  2019.  New Eng J Med.  381:503-505. PMCID: PMC6697094.

Luna BM, Yan J, Reyna Z, Moon E, Nielsen TB, Reza H, Bonomo R, Louie A, Drusano G, Bulitta J, She R, Spellberg B.  Natural history of Acinetobacter baumannii infection in mice.  2019.  PLoS One.  14(7):e0219824. PMCID: PMC6638954.

Spellberg B, Nielsen TB, Gilbert DN, Shorr AF, Brass EP.  Ensuring Sustainability of Needed Antibiotics: Aiming for the DART Board.  2019.  Ann Int Med.  171:580-2.

Wilson BM, Bessesen MT, Doros G, Brown ST, Saade E, Hermos J, Perez F, Skalweit M, Spellberg B, Bonomo RA.  Adjunctive Rifampin Therapy For Diabetic Foot Osteomyelitis in the Veterans Health Administration.  2019.  JAMA Network Open.  2(11):e1916003.  PMCID: PMCID: PMC6902814.

Spellberg B.  Are echinocandins superior in efficacy to azoles?  2020.  Clin Infect Dis.  70(9):2020-2021.

Tolles J, Waterman G, Coffey CE Jr, Sandoval R, Fleischman RJ, Hess M, Sarff L, Lewis RJ, Spellberg B, on behalf of the BRAVE Study Group.  The Bed Rest Avoidance (BRAVE) Study.  PLoS One.  2020.  15(1):e0226332.

Shorr AF, Zilberberg M, Spellberg B, Kollef M.  Microbiologic Failure Despite Clinical Cure in Pneumonia: Cum Hoc and Post Hoc Ergo Propter Hoc.  2020.  Clin Infect Dis.  ePub.

Spellberg B, Chambers HF, Musher DM, Walsh TL, Bayer AS.  Evaluation of a Paradigm Shift From Intravenous Antibiotics to Oral Step-Down Therapy for the Treatment of Infective Endocarditis: A Narrative Review.  2020  JAMA Int Med.  180(5):769-777.  PMCID: PMC7483894.

Spellberg B, Haddix M, Lee R, Butler-Wu S, Holtom P, Yee H, Gounder P.  Community Prevalence of SARS-CoV-2 Among Patients with Influenza-Like Illnesses Presenting to a Los Angeles Medical Center in March 2020.  2020.  JAMA.  323(19):1966-7.  PMCID: PMCID: PMC7110920.

Maeusli M, Lee B, Miller S, Reyna Z, Lu P, Yan J, Ulhaq A, Skandalis N, Spellberg B, Luna B. A. baylyi horizontal gene transfer to E. coli on lettuce and subsequent antibiotic resistance transmission to the gut microbiome.  2020.  mSphere.  5(3):e00329-20.  PMCID: PMCID: PMC7253597.


Luna B, Trebosc V, Lee B, Bakowski M, Ulhaq A, Yan J, Lu P, Cheng J, Nielsen T, Lim J, Ketphan W, Eoh H, McNamara C, Skandalis N, She R, Kemmer C, Lociuro S, Dale GE, Spellberg B.  A Novel Screen Unmasks Rifabutin Hyperactivity for XDR Acinetobacter baumannii.  Nature Microbiol.  5(9):1134-1143.


Spellberg B.  Alignment with Market Forces: The “Re-Whithering” of Infectious Diseases.  2020.  Open Forum Infect Dis.  20;7(8):ofaa245.  PMCID: PMC7397831.


Wright WF, Jorgenson SCJ, Spellberg B.  Heaping the Pelion of Vancomycin on the Ossa of MRSA: Back to Basics in Clinical Care and Guidelines.  2020.  Clin Infect Dis.  ePub.


Phillips MC, Wald-Dickler N, Loomis K, Luna BM, Spellberg B.  2020.  Pharmacology, Dosing, and Side Effects of Rifabutin as a Possible Therapy for Antibiotic-Resistant Acinetobacter Infections.  Open Forum Infectious Diseases.  7(11):ofaa460.


Luu A, Dominguez F, Yeshoua B, Vo C, Nallapa S, Chung D, Wald-Dickler N, Butler-Wu SM, Khaleel H, Chang K, Canamar C, Holtom P, Spellberg B.  Reducing Catheter Associated Urinary Tract Infections via Cost-Saving Diagnostic Stewardship.  Clin Infect Dis.  ePub.

Spellberg B, Nielsen TB, Casadevall A.  Antibodies, Immunity, and COVID-19.  JAMA Internal Medicine.  ePub.

Cheng J, Yan J, Reyna Z, Slarve M, Lu P, Spellberg B, Luna B.  Synergistic rifabutin and colistin reduce emergence of resistance when treating Acinetobacter baumannii.  Antimicrob Agents Chemother.  2021.  ePub.

Talyansky Y, Nielsen TB, Yan J, Carlino-Macdonald U, Di Venanzio G, Chakravorty S, Ulhaq A, Feldman MF, Russo TA, Vinogradov E, Luna B, Wright MS, Adams MD, Spellberg B.  Capsule carbohydrate structure determines virulence in Acinetobacter baumannii.  PLoS Pathogens.  2021.  7:e1009291.

ACTIV-3/TICO LY-CoV555 Study Group, Lundgren JD, Grund B, Barkauskas CE, et al.  A Neutralizing Monoclonal Antibody for Hospitalized Patients with Covid-19.  New Eng J Med.  2021.  384(10):905-914.


Minejima E, Wang J, Boettcher S, Liu L, Lou M, She RC, Wenzel SL, Spellberg B, Wong-Beringer A.  Distance Between Home and the Admitting Hospital and Its Effect on Survival of Low Socioeconomic Status Population With Staphylococcus aureus Bacteremia.  Public Health Rep.  2021.  ePub.


Jorgensen S, Spellberg B, Shorr AF, Wright WF.  Should Therapeutic Drug Monitoring Based on the Vancomycin Area Under the Concentration-Time Curve Be Standard for Serious Methicillin-Resistant Staphylococcus aureus Infections? - No.  Clin Infect Dis.  ePub.


Banerjee J, Canamar CP, Voyageur C, Tangpraphaphorn S, Lemus A, Coffey Jr C, Wald-Dickler N, Holtom P, Shoenberger J, Bowdish M, Yee HF, Spellberg B.  Mortality and Readmission Rates Among Patients With COVID-19 After Discharge From Acute Care Setting With Supplemental Oxygen.  JAMA Open Network.  2021. 4(4):e213990.

Sargent RE, Sener SF, Amaya R, Vazquez E, Bowdish ME, Spellberg B.  SARS-CoV-2-related outcomes after surgical procedures on SARS-CoV-2-positive patients in a large, urban, safety net medical center.  Surg Open Sci.  2021.  ePub.

Centor RM, Lee RA, Spellberg B.  Web Exclusive. Annals On Call - The Right Antibiotic, for the Right Infection, and for the Right Duration.  Ann Int Med.  2021.  174(5):OC1.

Nielsen TB, Yan J, Luna BM, Talyansky Y, Slarve M, Bonomo RA, Spellberg B.  Monoclonal antibody requires immunomodulation for efficacy against Acinetobacter baumannii infection.  J Infect Dis.  2021.  ePub.

Wald-Dickler N, Holtom PD, Phillips MC, Centor RM, Lee RA, Baden R, Spellberg B.  Oral Is the New IV--Challenging Decades of Blood and Bone Infection Dogma: A Systematic Review.  Am J Med. ePub.

Spellberg B, Wright WF, Shaneyfelt T, Centor RM.  The Future of Medical Guidelines—Standardizing Clinical Care with the Humility of Uncertainty.  Ann Int Med.  2021.  ePub.


Spellberg B, Shorr AF.  Opinion-Based Recommendations: Beware the Tyranny of Experts.  Open Forum Infect Dis.  ePub.